Dejan Gagoski
Keywords: Antibody engineering, Data analysis and ML, Immunotherapies
At the Lai lab, I am combining protein display-based selections and deep sequencing for antibody and antigen development.
Previously, I worked on developing methodologies for higher throughput of protein characterization, including cell-free protein expression, super-resolution microscopy, protein selections and deep sequencing.
I look forward to applying the all the used methods for more efficient development of antibodies and antigens for immunizations and immunotherapies. Outside the lab, I enjoy cultural events, socializing, and enjoying all that a big city can offer.
Previous Education
Ph.D. Synthetic Biology, Enzymes, & Analytical Biochemistry, University of Queensland, Brisbane, Australia, 2016
Dipl. Biology, University of Kassel, Kassel, Hesse, Germany, 2010
Selected Publications
Gagoski D, Rube TH, Melo L, Rastogi C, Li X, Voleti R, Shah NH and Bussemaker HJ; Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression; Pro. Sci. 2025 Nov; doi: 10.1002/pro.70317.
Li A, Voleti R, Lee M, Gagoski D, Shah NH; High-throughput profiling of sequence recognition by tyrosine kinases and SH2 domains using bacterial peptide display; Elife 2023 Mar; doi: 10.7554/eLife.82345.
Ayva CE, Fiorito MM, Guo Z, Edwardraja S, Kaczmarski JA, Gagoski D, Walden P, Johnston WA, Jackson CJ, Nebl T, Alexandrov K; Exploring Performance Parameters of Artificial Allosteric Protein Switches; J Mol Biol 2022; doi: 10.1016/j.jmb.2022.167678.